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Storb, Ursula

One or more keywords matched the following items that are connected to Storb, Ursula

Item Type	Name
Concept	Base Sequence
Academic Article	PU.1 is a component of a multiprotein complex which binds an essential site in the murine immunoglobulin lambda 2-4 enhancer.
Academic Article	Influence of CpG methylation and target spacing on V(D)J recombination in a transgenic substrate.
Academic Article	The mechanism of somatic hypermutation studied with transgenic and transfected target genes.
Academic Article	Somatic hypermutation of immunoglobulin genes is linked to transcription initiation.
Academic Article	N region diversity of a transgenic substrate in fetal and adult lymphoid cells.
Academic Article	Identification and characterization of the murine Rag1 promoter.
Academic Article	Somatic hypermutation of an artificial test substrate within an Ig kappa transgene.
Academic Article	The composition of coding joints formed in V(D)J recombination is strongly affected by the nucleotide sequence of the coding ends and their relationship to the recombination signal sequences.
Academic Article	Mef2 proteins, required for muscle differentiation, bind an essential site in the Ig lambda enhancer.
Academic Article	A hypermutable insert in an immunoglobulin transgene contains hotspots of somatic mutation and sequences predicting highly stable structures in the RNA transcript.
Academic Article	Hypomethylation is necessary but not sufficient for V(D)J recombination within a transgenic substrate.
Academic Article	The TATA binding protein, c-Myc and survivin genes are not somatically hypermutated, while Ig and BCL6 genes are hypermutated in human memory B cells.
Academic Article	Insertion of phosphoglycerine kinase (PGK)-neo 5' of Jlambda1 dramatically enhances VJlambda1 rearrangement.
Academic Article	Signal joint formation is inhibited in murine scid preB cells and fibroblasts in substrates with homopolymeric coding ends.
Academic Article	Analysis of a T cell receptor gene as a target of the somatic hypermutation mechanism.
Academic Article	Two conserved essential motifs of the murine immunoglobulin lambda enhancers bind B-cell-specific factors.
Academic Article	The E box motif CAGGTG enhances somatic hypermutation without enhancing transcription.
Academic Article	Mutation pattern of immunoglobulin transgenes is compatible with a model of somatic hypermutation in which targeting of the mutator is linked to the direction of DNA replication.
Academic Article	Identification and localization of an enhancer for the human lambda L chain Ig gene complex.
Academic Article	Activation-induced cytidine deaminase (AID) can target both DNA strands when the DNA is supercoiled.
Academic Article	Targeting of the activation-induced cytosine deaminase is strongly influenced by the sequence and structure of the targeted DNA.
Academic Article	A novel enhancer in the immunoglobulin lambda locus is duplicated and functionally independent of NF kappa B.
Academic Article	Alkyladenine DNA glycosylase (Aag) in somatic hypermutation and class switch recombination.
Academic Article	Differential splicing of thymosin beta 4 mRNA.
Academic Article	Analysis of somatic mutations in kappa transgenes.
Academic Article	Asymmetric processing of coding ends and the effect of coding end nucleotide composition on V(D)J recombination.
Academic Article	Misalignment of V and J gene segments resulting in a nonfunctional immunoglobulin gene.
Academic Article	Allelic exclusion and control of endogenous immunoglobulin gene rearrangement in kappa transgenic mice.
Academic Article	Structural alterations in J regions of mouse immunoglobulin lambda genes are associated with differential gene expression.
Academic Article	Sequences related to immunoglobulin kappa chain messenger RNA in T cells.
Academic Article	Immunoglobulin gene 'remnant' DNA--implications for antibody gene recombination.
Academic Article	Somatic mutation of immunoglobulin light-chain variable-region genes.
Academic Article	Pip, a novel IRF family member, is a lymphoid-specific, PU.1-dependent transcriptional activator.
Academic Article	lambda 5, but not mu, is required for B cell maturation in a unique gamma 2b transgenic mouse line.
Academic Article	Fusion of a scid pre-B cells with a wild type (myeloma) B cell results in correct rearrangement of a V(D)J recombination substrate.
Academic Article	Heterogeneity of the 3' portion of sequences related to immunoglobulin kappa-chain mRNA.
Academic Article	RNA sequences homologous to the 3' portion of immunoglobulin alpha-chain mRNA in thymus-derived lymphocytes.
Academic Article	Sequences of immunoglobulin lambda 1 genes in a lambda 1 defective mouse strain.
Academic Article	Evolution of mouse immunoglobulin lambda genes.
Academic Article	Expression of lambda and kappa genes can occur in all B cells and is initiated around the same pre-B-cell developmental stage.
Academic Article	Attracting AID to targets of somatic hypermutation.
Academic Article	Crossing the SJL lambda locus into kappa-knockout mice reveals a dysfunction of the lambda 1-containing immunoglobulin receptor in B cell differentiation.
Academic Article	Different mismatch repair deficiencies all have the same effects on somatic hypermutation: intact primary mechanism accompanied by secondary modifications.
Academic Article	Molecular aspects of somatic hypermutation of immunoglobulin genes.
Academic Article	The 3' Igkappa enhancer contains RNA polymerase II promoters: implications for endogenous and transgenic kappa gene expression.
Grant	CONTROL OF IMMUNOGLOBULIN SYNTHESIS

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